Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trovafloxacin4 SCHEMBL9184555 | 0.84 | DPP4 (0.72) | DPP4CHRM2DRD1LMNAKDM4E | |
| Trovafloxacin4 SCHEMBL9178854 | 0.84 | DPP4 (0.72) | DPP4CHRM2DRD1LMNAKDM4E | |
| Trovafloxacin4 SCHEMBL9178841 | 0.84 | DPP4 (0.72) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9838735 | 0.83 | KMT2A (0.69) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL13576371 | 0.83 | KMT2A (0.69) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL4575476 | 0.83 | KMT2A (0.69) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL11022634 | 0.83 | DPP4 (0.68) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL10652931 | 0.83 | KMT2A (0.68) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL20394712 | 0.82 | DPP4 (0.67) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL8385866 | 0.82 | DPP4 (0.74) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017581-A | Pyridonecarboxylic acids and their anti-bacterial compositions | SHIONOGI & CO., LTD. (JP) | 1991-05-21 | — | — | US | claimed |
| EP-0362759-A1 | Pyridonecarboxylic acids | SHIONOGI & CO., LTD. (JP) | 1990-04-11 | — | — | EP | claimed |
| US-5017581-A | Pyridonecarboxylic acids and their anti-bacterial compositions | SHIONOGI & CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0362759-A1 | Pyridonecarboxylic acids | SHIONOGI & CO., LTD. (JP) | 1990-04-11 | — | — | EP | disclosed |