Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | DPP4 | P27487 | 6/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.63 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838735 | 1.00 | KMT2A (0.69) | KMT2ADPP4CHRM2ALDH1A1POLB | |
| SCHEMBL13576371 | 1.00 | KMT2A (0.69) | KMT2ADPP4CHRM2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL10652931 | 0.99 | KMT2A (0.68) | KMT2ADPP4CHRM2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL10824865 | 0.95 | KMT2A (0.66) | KMT2ADPP4CHRM2ALDH1A1POLB | |
| SCHEMBL11022634 | 0.94 | DPP4 (0.68) | KMT2ADPP4CHRM2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL20394712 | 0.93 | DPP4 (0.67) | KMT2ADPP4CHRM2ALDH1A1POLB | |
| SCHEMBL9177508 | 0.89 | DPP4 (0.65) | KMT2ADPP4CHRM2ALDH1A1POLB | |
| SCHEMBL9177523 | 0.89 | DPP4 (0.65) | KMT2ADPP4CHRM2ALDH1A1POLB | |
| SCHEMBL9177514 | 0.89 | DPP4 (0.65) | KMT2ADPP4CHRM2ALDH1A1POLB | |
| SCHEMBL10928412 | 0.89 | DPP4 (0.64) | KMT2ADPP4CHRM2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305048-A2 | INHIBITORS OF CELLULAR EFFLUX PUMPS OF MICROBES | Wockhardt Limited (IN) | 2003-05-02 | — | — | EP | claimed |
| US-20020177559-A1 | Quinolone derivatives | WOCKHARDT LIMITED | 2002-11-28 | — | — | US | claimed |
| WO-2002009758-A2 | INHIBITORS OF CELLULAR EFFLUX PUMPS OF MICROBES | WOCKHARDT LIMITED (IN) | 2002-02-07 | — | — | WO | claimed |
| EP-0235589-B1 | USE OF QUINOLONE AND NAPHTHYRIDINE ANTIBIOTICS FOR THE MANUFACTURE OF OPHTHALMIC MEDICAMENTS | WARNER-LAMBERT COMPANY (US) | 1992-10-28 | — | — | EP | claimed |
| EP-0394685-A2 | (S)-7-(3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid | WARNER-LAMBERT COMPANY (US) | 1990-10-31 | — | — | EP | claimed |
| US-4916141-A | ANTIBACTERIAL | WARNER-LAMBERT COMPANY (US) | 1990-04-10 | — | — | US | claimed |
| US-4851415-A | TOPICAL ADMINISTRATION | WARNER-LAMBERT COMPANY (US) | 1989-07-25 | — | — | US | claimed |
| EP-0235589-A2 | Use of quinolone and naphthyridine antibiotics for the manufacture of ophthalmic medicaments | WARNER-LAMBERT COMPANY (US) | 1987-09-09 | — | — | EP | claimed |
| US-4649144-A | Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | claimed |
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | claimed |
| EP-0153163-A2 | 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | claimed |
| EP-0132845-A2 | Novel 1,8-Naphthyridine derivatives, and process for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1985-02-13 | — | — | EP | claimed |
| JP-60028978-A | — | — | None | — | — | JP | disclosed |
| JP-2289568-A | — | — | None | — | — | JP | disclosed |
| US-20250295790-A1 | LECTIN-TARGETING CONJUGATES | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-25 | — | — | US | disclosed |
| EP-4444355-A2 | LECTIN-TARGETING CONJUGATES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2024-10-16 | — | — | EP | disclosed |
| EP-0160578-A1 | 1,8-Naphthyridine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0153163-A2 | 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| JP-S6028978-A | 1,8-NAPHTHYRIDINE DERIVATIVE | DAINIPPON PHARMACEUT CO LTD | 1985-02-14 | — | — | JP | disclosed |
| EP-0132845-A2 | Novel 1,8-Naphthyridine derivatives, and process for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1985-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250295790-A1 | LECTIN-TARGETING CONJUGATES | MASP2, LGALS3BP, LGALS1 | KMT2A 4324/4885DPP4 161/4885CHRM2 3211/4885 |
| US-20020177559-A1 | Quinolone derivatives | ABCB11, ABCB1, ABCG2 | KMT2A 4343/4885DPP4 819/4885CHRM2 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.