SCHEMBL9789528

SCHEMBL9789528

O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1.O=C(O)c1ccc(C(=O)OC(=O)c2ccc(C(=O)O)cc2C(=O)O)c(C(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.56
HSD17B10 Q99714 2/20 0.53
CDC25A P30304 1/20 0.53
CDC25B P30305 1/20 0.53
POLB P06746 4/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
APEX1 P27695 2/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
LMNA P02545 1/20 0.44
RAB9A P51151 1/20 0.44
MYC P01106 1/20 0.43
ALDH1A1 P00352 3/20 0.43
TSHR P16473 2/20 0.42
TP53 P04637 1/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA4 P22748 2/20 0.42
CA6 P23280 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22457 0.98 KDM4E (0.53) KDM4EHSD17B10CDC25ACDC25BPOLB
Hydrochloric Acid SCHEMBL347000 0.96 KDM4E (0.52) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL9719672 0.96 KDM4E (0.52) KDM4EHSD17B10CDC25ACDC25BPOLB
Ammonia Solution, Strong SCHEMBL3951628 0.96 KDM4E (0.52) KDM4EHSD17B10CDC25ACDC25BPOLB
Bromide SCHEMBL8174299 0.96 KDM4E (0.52) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL29436298 0.94 KDM4E (0.50) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL29979349 0.94 KDM4E (0.50) KDM4EHSD17B10CDC25ACDC25BPOLB
Cyanide SCHEMBL9847521 0.92 KDM4E (0.49) KDM4EHSD17B10CDC25ACDC25BPOLB
Urea SCHEMBL5149485 0.92 KDM4E (0.49) KDM4EHSD17B10CDC25ACDC25BPOLB
Acetic Acid SCHEMBL22444416 0.92 KDM4E (0.49) KDM4EHSD17B10CDC25ACDC25BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132940-A1 MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL 万华化学集团股份有限公司 2020-07-02 WO disclosed
EP-3060610-B1 ANTI-STAINING COATING COMPOSITION PPG IND OHIO INC (US) 2018-02-21 EP disclosed
US-20160264298-A1 Anti-Staining Coating Composition PPG INDUSTRIES OHIO, INC. 2016-09-15 US disclosed
EP-3060610-A1 ANTI-STAINING COATING COMPOSITION PPG Industries Ohio, Inc. (US) 2016-08-31 EP disclosed
WO-2015059253-A1 ANTI-STAINING COATING COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2015-04-30 WO disclosed
EP-2865721-A1 A coating composition PPG Industries Ohio Inc. (US) 2015-04-29 EP disclosed
US-5068395-A Trimellitic acid polyester ether with polyethylene terephthalate modified with fatty acid as a plasticizer for polyvinyl chloride AMOCO CORPORATION (US) 1991-11-26 US disclosed