Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | BAX | Q07812 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402154 | 0.95 | LTA4H (0.60) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL29860094 | 0.95 | LTA4H (0.60) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL9515088 | 0.95 | LTA4H (0.60) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL15869781 | 0.87 | CYP2A6 (0.58) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL27670582 | 0.87 | LTA4H (0.68) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL4516331 | 0.87 | CYP2A6 (0.58) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL3895815 | 0.86 | LTA4H (0.71) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL395026 | 0.86 | CYP1A2 (0.64) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL9216135 | 0.86 | LTA4H (0.71) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL9217508 | 0.86 | LTA4H (0.71) | LTA4HTSHRMAOANR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037936-A | Bis(acid chloride) terminated polyaryl ether ketone oligomer | AMOCO CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| US-4997902-A | Polyether ketone polymers | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-05 | — | — | US | disclosed |
| US-4861915-A | Poly (aryl ether ketone) block copolymers | AMOCO CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0327980-A2 | High-temperature-resistant polyaryl ether having an enhanced processability | BASF Aktiengesellschaft (DE) | 1989-08-16 | — | — | EP | disclosed |
| US-4786694-A | Poly(aryl ether ketone) block copolymers | AMOCO CORPORATION (US) | 1988-11-22 | — | — | US | disclosed |