⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195894 | 0.80 | — | — | |
| SCHEMBL16597642 | 0.74 | RAB9A (0.63) | — | |
| SCHEMBL15871027 | 0.74 | RAB9A (0.63) | — | |
| SCHEMBL28376686 | 0.73 | RAB9A (0.43) | — | |
| SCHEMBL17185663 | 0.72 | — | — | |
| SCHEMBL5623070 | 0.70 | — | — | |
| SCHEMBL445202 | 0.70 | — | — | |
| SCHEMBL29847083 | 0.70 | — | — | |
| SCHEMBL193827 | 0.70 | — | — | |
| SCHEMBL11102261 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234062-A | Pyrazinylimidazole compound, weldable protective agent, preparation method and application of pyrazinylimidazole compound and weldable protective agent | 赣州市贝加尔电子材料有限公司 | 2021-08-10 | — | — | CN | claimed |
| CN-106998685-A | 14-membered ketolides and methods of making and using the same | 哈佛大学的校长及成员们 | 2017-08-01 | — | — | CN | claimed |
| CN-105246334-A | Macrolides and methods of making and using the same | HARVARD COLLEGE | 2016-01-13 | — | — | CN | claimed |
| CN-102858743-B | Spiro-condensed cyclohexane derivatives as HSL inhibitors useful for the treatment of diabetes | HOFFMANN LA ROCHE | 2015-06-10 | — | — | CN | claimed |
| EP-2435420-B1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-04-03 | — | — | EP | claimed |
| CN-102858743-A | Spiro-condensed cyclohexane derivatives as HSL inhibitors useful for the treatment of diabetes | HOFFMANN LA ROCHE | 2013-01-02 | — | — | CN | claimed |
| US-20120190687-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG | 2012-07-26 | — | — | US | claimed |
| CN-102421777-A | Azacyclospiro derivatives as HSL inhibitors | HOFFMANN LA ROCHE | 2012-04-18 | — | — | CN | claimed |
| CN-1863770-B | Cyclic amine BASE-1 inhibitors having a heterocyclic substituent | SCHERING CORP | 2011-05-25 | — | — | CN | claimed |
| CN-1703414-A | Novel imidazopyridines as cyclin dependent kinase inhibitors | SCHERING CORP (US) | 2005-11-30 | — | — | CN | claimed |
| CN-1522256-A | Novel substituted tetracyclic imidazole derivatives, processes for their preparation, pharamaceutical compositions comprising them and their use as a medicine | 詹森药业有限公司 | 2004-08-18 | — | — | CN | claimed |
| CN-1454086-A | High affinity small molecule C5A receptor modulators | NEUROGEN CORP (US) | 2003-11-05 | — | — | CN | claimed |
| EP-0773930-A1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LIMITED (GB) | 1997-05-21 | — | — | EP | claimed |
| CN-109285957-B | Organic light emitting device | 三星显示有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-113234062-B | Pyrazinylimidazole compound, weldable protective agent, preparation method and application of pyrazinylimidazole compound and weldable protective agent | 赣州市贝加尔电子材料有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113234062-A | Pyrazinylimidazole compound, weldable protective agent, preparation method and application of pyrazinylimidazole compound and weldable protective agent | 赣州市贝加尔电子材料有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-1454086-A | High affinity small molecule C5A receptor modulators | NEUROGEN CORP (US) | 2003-11-05 | — | — | CN | disclosed |
| CN-1039999-C | Vasopressin antagonist and oxytocin antagonist, process for their preparation and pharmaceutical compositions containing them | OTSUKA CHEMICAL CO LTD (JP) | 1998-09-30 | — | — | CN | disclosed |
| CN-1183277-A | Vasopressin antagonist and oxytocin antagonist | OTASUKA PHARMACEUTICAL CO LTD (JP) | 1998-06-03 | — | — | CN | disclosed |
| CN-1098716-A | Vasopressin antagonists and oxytocin antagonists | OTSUKA CHEMICAL CO LTD (JP) | 1995-02-15 | — | — | CN | disclosed |