Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790654 | 1.00 | PTGS1 (0.45) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9790656 | 1.00 | PTGS1 (0.45) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9790817 | 0.88 | CAMK2A (0.44) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9790818 | 0.88 | CAMK2A (0.44) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9790676 | 0.88 | CAMK2A (0.44) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9790853 | 0.88 | CAMK2A (0.44) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9790681 | 0.88 | CAMK2A (0.44) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9790856 | 0.88 | CAMK2A (0.44) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9790703 | 0.86 | PTGS1 (0.42) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9790707 | 0.86 | PTGS1 (0.42) | PTGS1PTGS2OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057513-A | Platelet activating factor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0399424-A1 | Thiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |