Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790856 | 1.00 | CAMK2A (0.44) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9790818 | 1.00 | CAMK2A (0.44) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9790681 | 1.00 | CAMK2A (0.44) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9790676 | 1.00 | CAMK2A (0.44) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9790817 | 1.00 | CAMK2A (0.44) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9790703 | 0.88 | PTGS1 (0.42) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9790650 | 0.88 | PTGS1 (0.45) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9790656 | 0.88 | PTGS1 (0.45) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9790707 | 0.88 | PTGS1 (0.42) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9790654 | 0.88 | PTGS1 (0.45) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057513-A | Platelet activating factor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0399424-A1 | Thiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |