Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 11/20 | 1.00 |
| ▸ | CDK2 | P24941 | 7/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CCNH | P51946 | 1/20 | 0.45 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164309 | 0.80 | FDPS (1.00) | FDPSSMN1; SMN2 | |
| SCHEMBL9790756 | 0.79 | FDPS (0.97) | FDPSSMN1; SMN2 | |
| SCHEMBL9790803 | 0.77 | FDPS (0.66) | FDPSFDFT1 | |
| SCHEMBL7945367 | 0.76 | FDPS (1.00) | FDPSCDK2CCNE1CDK5FDFT1 | |
| SCHEMBL9790749 | 0.74 | FDPS (1.00) | FDPSCDK2CCNE1CDK5FDFT1 | |
| SCHEMBL9790811 | 0.72 | FDPS (0.61) | FDPSCDK2CCNE1CDK5 | |
| SCHEMBL7163557 | 0.72 | FDPS (1.00) | FDPSCDK2CCNE1CDK5SMN1; SMN2 | |
| SCHEMBL681610 | 0.71 | CDK2 (0.73) | FDPSCDK2CCNE1CDK5CCNT1 | |
| SCHEMBL9790770 | 0.71 | FDPS (0.60) | FDPSCDK2CCNE1CDK5 | |
| SCHEMBL9790768 | 0.71 | FDPS (0.80) | FDPSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057505-A | Treatment of illnesses attributed to calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | claimed |
| US-5057505-A | Treatment of illnesses attributed to calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |