Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790558 | 0.86 | ALDH1A1 (0.36) | ALDH1A1HPGDPTGS2PTGS1GRIN2B | |
| SCHEMBL9790532 | 0.85 | ALDH1A1 (0.42) | ALDH1A1HPGDGAAKMT2ANISCH | |
| SCHEMBL9790549 | 0.85 | HPGD (0.40) | ALDH1A1HPGDNPC1RAB9ANISCH | |
| SCHEMBL9790438 | 0.82 | HPGD (0.39) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL9790616 | 0.82 | ATM (0.43) | ALDH1A1HPGDMEN1KMT2AGRIN2B | |
| SCHEMBL9790547 | 0.82 | ALDH1A1 (0.40) | ALDH1A1HPGDMEN1GAAKMT2A | |
| SCHEMBL9790569 | 0.81 | NPC1 (0.51) | ALDH1A1HPGDNPC1RAB9AGRIN2B | |
| SCHEMBL9790579 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HPGDRAB9AMEN1KMT2A | |
| SCHEMBL9790661 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HPGDPTGS2NPC1RAB9A | |
| SCHEMBL9790565 | 0.80 | MAPT (0.45) | ALDH1A1HPGDNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994569-A | Cholecystokinin antagonists | RHONE-POULENC SANTE (FR) | 1991-02-19 | — | — | US | disclosed |