Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489674 | 0.84 | MEN1 (0.36) | MEN1KMT2AKDM4C | |
| SCHEMBL10576592 | 0.84 | MEN1 (0.38) | MEN1KMT2AKDM4CGRM5 | |
| SCHEMBL10700390 | 0.83 | MEN1 (0.33) | MEN1KMT2AKDM4CGRM5 | |
| SCHEMBL7533743 | 0.81 | MEN1 (0.35) | MEN1KMT2AKDM4CGRM5 | |
| SCHEMBL11268292 | 0.80 | MEN1 (0.42) | MEN1KMT2AKDM4C | |
| SCHEMBL5369982 | 0.79 | MEN1 (0.34) | MEN1KMT2AKDM4CGRM5 | |
| SCHEMBL11813613 | 0.79 | MEN1 (0.35) | MEN1KMT2AKDM4CGRM5 | |
| SCHEMBL2989785 | 0.79 | MEN1 (0.35) | MEN1KMT2AKDM4CGRM5 | |
| SCHEMBL11824286 | 0.78 | — | — | |
| SCHEMBL8769967 | 0.78 | MEN1 (0.33) | MEN1KMT2AKDM4CGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063229-A | Antiinflammatory agents | ROUSSEL ULCAF (FR) | 1991-11-05 | — | — | US | disclosed |
| US-4895866-A | Anti-inflammatory imidazole compounds | ROUSSEL UCLAF (FR) | 1990-01-23 | — | — | US | disclosed |
| US-4810828-A | ANTIARTHRITIC, PSORIASIS | ROUSSEL UCLAF (FR) | 1989-03-07 | — | — | US | disclosed |
| US-4108851-A | 3β,17-Dihydroxy-5α,17α-pregn-20-ene-21-carboxylic acid γ-lactone and esters thereof | G. D. SEARLE & CO. (US) | 1978-08-22 | — | — | US | disclosed |