Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 9/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303056 | 0.87 | SNCA (0.44) | BCHECYP2D6HTR1ADRD3CHRM2 | |
| SCHEMBL627482 | 0.78 | MAOA (0.58) | MAOAPTGS1PTGS2BCHECYP2D6 | |
| SCHEMBL30184394 | 0.78 | MAOA (0.58) | MAOAPTGS1PTGS2BCHECYP2D6 | |
| SCHEMBL24806907 | 0.75 | MAOA (0.54) | MAOAPTGS1PTGS2BCHECYP2D6 | |
| SCHEMBL8142099 | 0.75 | PTGS1 (0.59) | MAOAPTGS1PTGS2BCHECYP2D6 | |
| SCHEMBL2921643 | 0.75 | MAOA (0.54) | MAOAPTGS1PTGS2BCHECYP2D6 | |
| SCHEMBL12386881 | 0.72 | PTGS1 (0.51) | MAOAPTGS1PTGS2BCHECYP2D6 | |
| SCHEMBL29833662 | 0.72 | BCHE (0.54) | MAOAPTGS1PTGS2BCHECYP2D6 | |
| SCHEMBL23374142 | 0.72 | MAOA (0.50) | MAOAPTGS1PTGS2BCHECYP2D6 | |
| SCHEMBL3696465 | 0.72 | BCHE (0.54) | MAOAPTGS1PTGS2BCHECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012110833-A2 | FLUORESCENCE MODULATORS | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2012-08-23 | — | — | WO | disclosed |
| US-5055213-A | Addition copolymers containing maleic anhydride monomer modifi ed by a phenothiazine derivative, napthtylamine or diphenylami ne; antideposit agents; dispersants; oxidation resistance | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-10-08 | — | — | US | disclosed |
| US-4225617-A | PSYCHOTROPIC AGENTS | LABORATOIRE L. LAFON (FR) | 1980-09-30 | — | — | US | disclosed |
| US-4209524-A | CENTRAL NERVOUS SYSTEM | LABORATOIRE L. LAFON (FR) | 1980-06-24 | — | — | US | disclosed |
| US-4209523-A | TREATMENT OF THE CENTRAL NERVOUS SYSTEM | LABORATOIRE L. LAFON (FR) | 1980-06-24 | — | — | US | disclosed |
| US-4183951-A | PSYCHOTROPIC AGENTS | LABORATOIRE L. LAFON (FR) | 1980-01-15 | — | — | US | disclosed |
| US-4152458-A | CENTRAL NERVOUS SYSTEM, PSYCHOTROPIC AGENTS | LABORATOIRE L. LAFON (FR) | 1979-05-01 | — | — | US | disclosed |
| US-4151300-A | CENTRAL NERVOUS SYSTEM, PSYCHOTROPIC | LABORATOIRE L. LAFON (FR) | 1979-04-24 | — | — | US | disclosed |
| US-4122186-A | PSYCHOTROPIC AGENTS | LABORATOIRE L. LAFON (FR) | 1978-10-24 | — | — | US | disclosed |