Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.33 |
| ▸ | PTGFR | P43088 | 2/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791025 | 1.00 | CYP3A4 (0.40) | CYP3A4CYP2D6CYP2C9LIPGPTGER3 | |
| SCHEMBL9791124 | 0.86 | PTGER3 (0.41) | CYP3A4CYP2D6CYP2C9LIPGPTGER3 | |
| SCHEMBL9791128 | 0.86 | PTGER3 (0.41) | CYP3A4CYP2D6CYP2C9LIPGPTGER3 | |
| Hydrochloric Acid SCHEMBL9791028 | 0.84 | PTGER3 (0.41) | CYP3A4CYP2D6CYP2C9LIPGPTGER3 | |
| SCHEMBL8702148 | 0.79 | PTGER3 (0.56) | PTGER3PTGER2PTGER4TBXA2RPTGDR | |
| SCHEMBL9725168 | 0.79 | LMNA (0.53) | CYP3A4CYP2D6CYP2C9LIPGPTGER3 | |
| SCHEMBL1542126 | 0.79 | PTGER3 (0.56) | PTGER3PTGER2PTGER4TBXA2RPTGDR | |
| SCHEMBL7530108 | 0.79 | PTGER3 (0.56) | PTGER3PTGER2PTGER4TBXA2RPTGDR | |
| SCHEMBL9788952 | 0.78 | PTGER3 (0.43) | CYP3A4CYP2D6CYP2C9LIPGPTGER3 | |
| SCHEMBL9337936 | 0.77 | SLC16A3 (0.38) | CYP3A4CYP2D6CYP2C9LIPGPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |