Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL9791137 | 0.98 | KDM4E (0.40) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL9791057 | 0.85 | KDM4E (0.44) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL9485334 | 0.85 | KDM4E (0.44) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL9791240 | 0.84 | KDM4E (0.44) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL9790960 | 0.81 | KDM4E (0.34) | KDM4EATMALDH1A1HTT | |
| SCHEMBL10482290 | 0.77 | KDM4E (0.41) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL8488769 | 0.76 | KDM4E (0.49) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL9791015 | 0.75 | SPHK2 (0.35) | KDM4EHRH3LIPGCYP2D6 | |
| Iodomethane SCHEMBL9790984 | 0.74 | SPHK2 (0.34) | KDM4EHRH3LIPGCYP2D6 | |
| SCHEMBL8491858 | 0.74 | KDM4E (0.47) | KDM4EATMALDH1A1HTTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028629-A | 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides | ELI LILLY AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |