Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | PDE5A | O76074 | 3/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791860 | 0.94 | KDM4E (0.38) | NPC1RAB9AHPGDNAMPTALDH1A1 | |
| SCHEMBL9791995 | 0.90 | KDM4E (0.35) | NPC1RAB9AHPGDNAMPTALDH1A1 | |
| SCHEMBL9791862 | 0.90 | KDM4E (0.35) | NPC1RAB9AHPGDNAMPTALDH1A1 | |
| SCHEMBL9791883 | 0.90 | KDM4E (0.37) | HPGDNAMPTALDH1A1 | |
| SCHEMBL9796151 | 0.90 | KDM4E (0.37) | HPGDNAMPTALDH1A1 | |
| SCHEMBL9791980 | 0.88 | PLK1 (0.47) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL9791917 | 0.88 | PLK1 (0.47) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL9841193 | 0.87 | L3MBTL1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9792015 | 0.86 | CA1 (0.45) | NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9792014 | 0.86 | CA1 (0.45) | NPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996334-A | Dibenzylidenesorbitols for gelatinizing oils and liquids, increasing transparency and rigidity in resins, improving viscosity of coatings and stabilizing emulsions | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-02-26 | — | — | US | disclosed |