Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792244 | 0.87 | MDM2 (0.35) | NPSR1GLAALDH1A1LMNAMAPT | |
| SCHEMBL9688851 | 0.82 | NPSR1 (0.48) | NPSR1GLAALDH1A1ALOX15LMNA | |
| SCHEMBL9792235 | 0.82 | CNR2 (0.33) | NPSR1GLAALDH1A1L3MBTL1MAPT | |
| SCHEMBL9792269 | 0.81 | HTT (0.40) | NPSR1GLALMNAHPGDHTT | |
| SCHEMBL9792291 | 0.80 | MEN1 (0.35) | ALDH1A1HPGDVNN1KMT2A | |
| SCHEMBL9792298 | 0.79 | GLA (0.32) | NPSR1GLA | |
| SCHEMBL9792243 | 0.78 | HPGD (0.36) | ALDH1A1ALOX15LMNAL3MBTL1MAPT | |
| SCHEMBL11060460 | 0.78 | HTT (0.38) | LMNAL3MBTL1MAPTHTTKMT2A | |
| SCHEMBL9792309 | 0.77 | GLA (0.30) | NPSR1GLA | |
| SCHEMBL9792202 | 0.77 | SMN1; SMN2 (0.46) | NPSR1GLAALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988822-A | Intermediates for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1,1-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1991-01-29 | — | — | US | disclosed |
| US-4873340-A | Process for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-A]pyrrole-1,1-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1989-10-10 | — | — | US | disclosed |