Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689996 | 0.84 | GLA (0.33) | GLANPSR1MDM2 | |
| SCHEMBL9792243 | 0.83 | HPGD (0.36) | — | |
| SCHEMBL9792244 | 0.80 | MDM2 (0.35) | GLANPSR1MDM2 | |
| SCHEMBL9792193 | 0.80 | HTT (0.41) | — | |
| SCHEMBL9792235 | 0.80 | CNR2 (0.33) | GLANPSR1 | |
| SCHEMBL9792224 | 0.79 | SMN1; SMN2 (0.38) | GLANPSR1 | |
| SCHEMBL9792186 | 0.79 | NPSR1 (0.47) | GLANPSR1 | |
| SCHEMBL9792282 | 0.77 | SMN1; SMN2 (0.36) | GLANPSR1 | |
| SCHEMBL9792202 | 0.77 | SMN1; SMN2 (0.46) | GLANPSR1 | |
| SCHEMBL9792291 | 0.76 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988822-A | Intermediates for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1,1-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1991-01-29 | — | — | US | disclosed |
| US-4873340-A | Process for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-A]pyrrole-1,1-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1989-10-10 | — | — | US | disclosed |