Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255858 | 1.00 | LMNA (0.39) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL9181705 | 0.91 | LMNA (0.36) | LMNAMEN1CYP3A4BLMKMT2A | |
| SCHEMBL9712212 | 0.88 | KDM4C (0.41) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL14176805 | 0.81 | KDM4C (0.35) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL11798360 | 0.80 | CA1 (0.40) | TSHRCA1 | |
| SCHEMBL9191489 | 0.78 | LMNA (0.43) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL24111239 | 0.76 | LMNA (0.42) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL23593919 | 0.76 | LMNA (0.42) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL19091709 | 0.76 | LMNA (0.42) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL24667932 | 0.76 | LMNA (0.42) | LMNAKDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985519-A | FLUOROOLEFIN, VINYL ESTER, HYDROXYL-CONTAINING ALLYL ETHER, AND CARBOXYL-CONTAINING MONOMER | CENTRAL GLASS COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | claimed |
| EP-0039060-A1 | A new method for preparation of anthracycline derivatives | Zaidanhojin Biseibutsu Kagaku Kenkyukai (JP) | 1981-11-04 | — | — | EP | claimed |
| US-3998602-A | ETCHING, GRAFT POLYMERIZATION IN SILVER SALT, CURING, ELECTROLESS DEPOSITION | HOROWITZ CARL | 1976-12-21 | — | — | US | claimed |
| US-4985519-A | FLUOROOLEFIN, VINYL ESTER, HYDROXYL-CONTAINING ALLYL ETHER, AND CARBOXYL-CONTAINING MONOMER | CENTRAL GLASS COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0039060-B1 | A NEW METHOD FOR PREPARATION OF ANTHRACYCLINE DERIVATIVES | Zaidanhojin Biseibutsu Kagaku Kenkyukai (JP) | 1986-08-06 | — | — | EP | disclosed |
| EP-0039060-A1 | A new method for preparation of anthracycline derivatives | Zaidanhojin Biseibutsu Kagaku Kenkyukai (JP) | 1981-11-04 | — | — | EP | disclosed |
| EP-0039060-A1 | A new method for preparation of anthracycline derivatives | Zaidanhojin Biseibutsu Kagaku Kenkyukai (JP) | 1981-11-04 | — | — | EP | disclosed |
| US-4009254-A | UNSYMMETRICAL ETHERS; SUNSCREEN AGENTS | COLGATE-PALMOLIVE COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-4006749-A | GRAFT POLYMERS, NICOTINE, PYRIDINE BASES | CONSOLIDATED CIGAR CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |
| US-3998602-A | ETCHING, GRAFT POLYMERIZATION IN SILVER SALT, CURING, ELECTROLESS DEPOSITION | HOROWITZ CARL | 1976-12-21 | — | — | US | disclosed |