Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ACP3 | P15309 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287934 | 0.81 | GSR (0.38) | LMNAGSRKMT2AACP3MAPK1 | |
| SCHEMBL12630728 | 0.79 | KMT2A (0.38) | ALDH1A1LMNAGSRNPC1ADAM17 | |
| SCHEMBL10601165 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAGSRAPPKMT2A | |
| SCHEMBL10598148 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAGSRAPPKMT2A | |
| SCHEMBL12630686 | 0.73 | KMT2A (0.35) | ALDH1A1LMNAGSRNPC1ADAM17 | |
| SCHEMBL10598153 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAGSRAPPKMT2A | |
| SCHEMBL10601629 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAGSRAPPKMT2A | |
| SCHEMBL10598468 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAGSRAPPKMT2A | |
| SCHEMBL10799704 | 0.73 | GSR (0.34) | ALDH1A1LMNAGSRNPC1ADAM17 | |
| SCHEMBL8753701 | 0.72 | GSR (0.37) | GSRKMT2AKDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110078623-A | A method of preparing 2,2 '-two -4,4 '-dinitro biphenyl of trifluoromethyl | 天津市均凯化工科技有限公司 | 2019-08-02 | — | — | CN | claimed |
| CN-106928079-B | Trefanocide haptens and its preparation method and application | 广东第二师范学院 | 2019-02-22 | — | — | CN | claimed |
| CN-108101789-A | A kind of preparation method of amino benzenes compounds | 苏州开元民生科技股份有限公司 | 2018-06-01 | — | — | CN | claimed |
| CN-106928079-A | Trefanocide haptens and its preparation method and application | 广东第二师范学院 | 2017-07-07 | — | — | CN | claimed |
| CN-104529839-B | 4,4 '-two [3,5-bis-(2-trifluoromethyl-4-aminophenoxyl) phenoxy group] diphenyl sulphone (DPS) and its preparation method and application | 吉林大学 | 2016-08-17 | — | — | CN | claimed |
| CN-104402731-A | Method utilizing catalytic hydrogenation synthesis of nitrobenzene compounds to prepare aniline compounds | YANTAI INST COASTAL ZONE RES CAS | 2015-03-11 | — | — | CN | claimed |
| JP-2045451-A | — | — | None | — | — | JP | disclosed |
| CN-110483303-A | A kind of 3- nitro -4- chlorobenzotrifluoride spent acid emission reduction new process | JIANGSU DAHUA CHEMICAL IND CO LTD | 2019-11-22 | — | — | CN | disclosed |
| CN-109535005-A | The preparation method of 2,2`- bis trifluoromethyl -4,4`- benzidine | 山东华夏神舟新材料有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-109111354-A | A kind of synthetic method of p-trifluoromethyl benzaldehyde | 阜新汉道化工有限责任公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-108929264-A | A kind of preparation method of fluazinam | 岳晟 | 2018-12-04 | — | — | CN | disclosed |
| CN-108503551-A | The solvent-free hydrogenation reduction process of mamino-trifluoromethyl benzene | 江苏大华化学工业有限公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-108503551-A | The solvent-free hydrogenation reduction process of mamino-trifluoromethyl benzene | 江苏大华化学工业有限公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-100371313-C | Process for preparing o-trifluoromethyl aniline | ZHEJIANG PROVINCE DONGYANG CIT (CN) | 2008-02-27 | — | — | CN | disclosed |
| CN-101102992-A | Process for producing 2,2'-bis(trifluoromethyl)-4,4'-diaminobiphenyl | AIR WATER CHEMICAL INC (JP) | 2008-01-09 | — | — | CN | disclosed |
| CN-1666974-A | Process for preparing o-trifluoromethyl aniline | ZHEJIANG PROVINCE DONGYANG CIT (CN) | 2005-09-14 | — | — | CN | disclosed |
| US-5053504-A | PROCESS FOR BENZAZEPINE INTERMEDIATES | E. R. SQUIBB & SONS, INC. (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0430031-A2 | Process for benzazepine intermediates | E.R. SQUIBB & SONS, INC. (US) | 1991-06-05 | — | — | EP | disclosed |
| JP-H0245451-A | PRODUCTION OF NITRORIFLUOROMETHYLTOLUENE | CENTRAL GLASS CO LTD | 1990-02-15 | — | — | JP | disclosed |
| US-4132737-A | ENZYME INHIBITORS | ELI LILLY AND COMPANY (US) | 1979-01-02 | — | — | US | disclosed |