SCHEMBL9793937

SCHEMBL9793937

CCC1(Cl)C(=O)C2CCC=CC21

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9809814 0.87
SCHEMBL9794176 0.84
SCHEMBL10384721 0.77 CYP19A1 (0.31)
SCHEMBL9793824 0.77 CYP19A1 (0.31)
SCHEMBL10384769 0.77 CYP19A1 (0.31)
SCHEMBL9750876 0.77
SCHEMBL9750824 0.77
SCHEMBL9750804 0.77
SCHEMBL9632638 0.70 CYP19A1 (0.31)
SCHEMBL9750992 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0255098-B1 Novel 8-(lower alkyl) bicyclo [4.2.0] octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1991-05-29 EP disclosed
US-4983627-A Treating atherosclerosis, thrombosis and vasospasms; anticholesterol,-secretory,-ulcer and hypotensive agents SYNTEX (U.S.A.) INC. (US) 1991-01-08 US disclosed
US-4927963-A Novel processes for the synthesis of certain bicyclo(4.2.0)octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1990-05-22 US disclosed
US-4735966-A ANTICOAGULANTS, VASODILATORS, HYPOTENSIVE AND ANTICHOLESTEROL AGENTS SYNTEX (U.S.A.) INC. (US) 1988-04-05 US disclosed
EP-0257609-A2 Novel substituted (4.2.0)Bicyclooctane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1988-03-02 EP disclosed
EP-0255098-A1 Novel 8-(lower alkyl) bicyclo [4.2.0] octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1988-02-03 EP disclosed
US-4678805-A Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1987-07-07 US disclosed