⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750824 | 1.00 | — | — | |
| SCHEMBL9750876 | 1.00 | — | — | |
| SCHEMBL10384769 | 0.81 | CYP19A1 (0.31) | — | |
| SCHEMBL9793824 | 0.81 | CYP19A1 (0.31) | — | |
| SCHEMBL10384721 | 0.81 | CYP19A1 (0.31) | — | |
| SCHEMBL4739025 | 0.79 | — | — | |
| SCHEMBL9793937 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL9750823 | 0.76 | — | — | |
| SCHEMBL9750992 | 0.76 | — | — | |
| SCHEMBL9809814 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257610-A2 | Process and intermediates for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives and for the synthesis of bicyclo(4.2.0)octane derivatives | SYNTEX (U.S.A.) INC. (US) | 1988-03-02 | — | — | EP | claimed |
| US-5049497-A | Novel process for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-09-17 | — | — | US | disclosed |
| US-4927963-A | Novel processes for the synthesis of certain bicyclo(4.2.0)octane derivatives with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4735966-A | ANTICOAGULANTS, VASODILATORS, HYPOTENSIVE AND ANTICHOLESTEROL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-04-05 | — | — | US | disclosed |
| EP-0257610-A2 | Process and intermediates for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives and for the synthesis of bicyclo(4.2.0)octane derivatives | SYNTEX (U.S.A.) INC. (US) | 1988-03-02 | — | — | EP | disclosed |
| EP-0257609-A2 | Novel substituted (4.2.0)Bicyclooctane derivatives with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1988-03-02 | — | — | EP | disclosed |