Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652515 | 1.00 | LMNA (0.50) | LMNATRPV1TRPA1KDM4CKDM4A | |
| SCHEMBL13075202 | 1.00 | LMNA (0.50) | LMNATRPV1TRPA1KDM4CKDM4A | |
| SCHEMBL6280786 | 1.00 | LMNA (0.50) | LMNATRPV1TRPA1KDM4CKDM4A | |
| SCHEMBL4363756 | 1.00 | LMNA (0.50) | LMNATRPV1TRPA1KDM4CKDM4A | |
| SCHEMBL5717469 | 1.00 | — | — | |
| Bromide SCHEMBL5343457 | 0.97 | LMNA (0.48) | LMNATRPV1TRPA1KDM4CKDM4A | |
| Hydrochloric Acid SCHEMBL5345632 | 0.97 | LMNA (0.48) | LMNATRPV1TRPA1KDM4CKDM4A | |
| SCHEMBL4814282 | 0.97 | — | — | |
| SCHEMBL2097116 | 0.87 | — | — | |
| SCHEMBL14840292 | 0.85 | HIF1A (0.41) | LMNATRPV1TRPA1HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248932-B1 | PROCESS FOR PREPARING POLYAMIDES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-01-09 | — | — | EP | disclosed |
| US-4754016-A | Process for preparing polyamide with organic phosphine/organic disulfide mixture condensing agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0248932-A1 | Process for preparing polyamides | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-12-16 | — | — | EP | disclosed |