Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794719 | 0.82 | ALDH1A1 (0.37) | MAPTKMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL9794721 | 0.82 | ALDH1A1 (0.37) | MAPTKMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL9794704 | 0.82 | KMT2A (0.49) | MAPTKMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL9794726 | 0.82 | KMT2A (0.49) | MAPTKMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL9794717 | 0.81 | MAPT (0.41) | MAPTKMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL9794727 | 0.78 | DAO (0.39) | MAPTKMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL9794712 | 0.77 | HDAC3 (0.42) | MAPTALDH1A1HPGDNPSR1TDP1 | |
| SCHEMBL9794715 | 0.77 | HDAC3 (0.42) | MAPTALDH1A1HPGDNPSR1TDP1 | |
| SCHEMBL9794708 | 0.73 | MAPT (0.53) | MAPTKMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL10743231 | 0.72 | KDM4E (0.49) | MAPTKMT2AALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996227-A | Administering nontoxic antitumor agents | UNIVERSITY OF CINCINNATI (US) | 1991-02-26 | — | — | US | disclosed |