Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.30 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9795133 | 1.00 | CA1 (0.41) | CA1CA2CA4TSHREPHX1 | |
| SCHEMBL9498434 | 0.96 | CA1 (0.44) | CA1CA2CA4TSHREPHX1 | |
| Oxalic Acid SCHEMBL9795235 | 0.85 | CA1 (0.36) | CA1CA2CA4TSHRSMN1; SMN2 | |
| Oxalic Acid SCHEMBL9795230 | 0.85 | CA1 (0.36) | CA1CA2CA4TSHRSMN1; SMN2 | |
| SCHEMBL9497838 | 0.80 | CA1 (0.39) | CA1CA2CA4TSHRSMN1; SMN2 | |
| SCHEMBL9795378 | 0.80 | CA1 (0.39) | CA1CA2CA4TSHRSMN1; SMN2 | |
| SCHEMBL9795142 | 0.76 | EPHX1 (0.31) | EPHX1SMN1; SMN2HSD17B10 | |
| SCHEMBL19909847 | 0.74 | ALDH1A1 (0.46) | CA1CA2CA4TSHREPHX1 | |
| SCHEMBL9795512 | 0.72 | CA1 (0.44) | CA1CA2CA4TSHREPHX1 | |
| SCHEMBL9795514 | 0.72 | CA1 (0.44) | CA1CA2CA4TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |