Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9795456 | 0.87 | MEN1 (0.36) | PTGS2PTGS1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9497957 | 0.85 | TSHR (0.41) | TSHRPTGS2PTGS1ALDH1A1CA12 | |
| SCHEMBL9501618 | 0.81 | KDM4E (0.37) | PTGS2PTGS1ALDH1A1CA12CA1 | |
| Fumaric Acid SCHEMBL9795581 | 0.79 | TSHR (0.36) | TSHRPTGS2PTGS1ALDH1A1KMT2A | |
| SCHEMBL10647896 | 0.76 | TSHR (0.43) | TSHRPTGS2PTGS1CA12CA1 | |
| SCHEMBL9499578 | 0.76 | MEN1 (0.37) | TSHRPTGS2PTGS1KMT2AMEN1 | |
| SCHEMBL9499926 | 0.75 | CA12 (0.38) | TSHRPTGS2PTGS1ALDH1A1CA12 | |
| SCHEMBL20381102 | 0.75 | NPC1 (0.40) | TSHRPTGS2PTGS1ALDH1A1KMT2A | |
| SCHEMBL20381100 | 0.75 | TDP1 (0.54) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL9497749 | 0.75 | MEN1 (0.34) | KMT2AMEN1CYP2C9ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |