Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499949 | 1.00 | EPHX2 (0.48) | EPHX2SMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL16741512 | 0.93 | SMN1; SMN2 (0.50) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL14174996 | 0.86 | ALDH1A1 (0.53) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL12819865 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL3225360 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL11822035 | 0.79 | EPHX2 (0.54) | EPHX2SMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL13573015 | 0.79 | EPHX2 (0.54) | EPHX2SMN1; SMN2HDAC3HDAC1HDAC2 | |
| Oxalic Acid SCHEMBL9795219 | 0.77 | EPHX2 (0.47) | EPHX2SMN1; SMN2ALDH1A1MAPTNPSR1 | |
| Oxalic Acid SCHEMBL9795222 | 0.77 | EPHX2 (0.47) | EPHX2SMN1; SMN2ALDH1A1MAPTNPSR1 | |
| SCHEMBL3227685 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |