Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9795050 | 0.95 | TSHR (0.37) | TSHRBCHEACHECA1CA2 | |
| SCHEMBL9500025 | 0.95 | TSHR (0.39) | TSHRBCHEACHECA1CA2 | |
| SCHEMBL10647896 | 0.87 | TSHR (0.43) | TSHRBCHEACHECA1CA2 | |
| SCHEMBL9498497 | 0.87 | CA1 (0.40) | TSHRBCHEACHECA1CA2 | |
| SCHEMBL9795292 | 0.85 | TSHR (0.39) | TSHRBCHEACHECA1CA2 | |
| SCHEMBL13396780 | 0.85 | CNR1 (0.43) | TSHRMEN1KMT2AHPGD | |
| Fumaric Acid SCHEMBL9795207 | 0.84 | SLC6A5 (0.37) | TSHRBCHEACHECA1CA2 | |
| SCHEMBL13396698 | 0.83 | ECE1 (0.42) | TSHRBCHEACHEMEN1KMT2A | |
| SCHEMBL9497895 | 0.83 | CYP2C19 (0.44) | TSHRBCHEACHECA1CA2 | |
| SCHEMBL10594419 | 0.81 | PTGS1 (0.36) | TSHRCA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |