Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSB | P07858 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795300 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2HSD17B10TSHRCTSKCTSB | |
| SCHEMBL9795308 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2HSD17B10TSHRCTSKCTSB | |
| SCHEMBL10460054 | 0.77 | HSD17B10 (0.70) | SMN1; SMN2HSD17B10CTSKCTSBEPHX1 | |
| SCHEMBL9795110 | 0.74 | CA1 (0.37) | SMN1; SMN2HSD17B10TSHRL3MBTL1 | |
| SCHEMBL9795116 | 0.74 | CA1 (0.37) | SMN1; SMN2HSD17B10TSHRL3MBTL1 | |
| Cyclohexanol SCHEMBL9499447 | 0.71 | CYP2D6 (0.41) | SMN1; SMN2HSD17B10TSHRL3MBTL1EPHX1 | |
| SCHEMBL5897128 | 0.70 | ALDH1A1 (0.36) | SMN1; SMN2TSHREPHX1GRM4 | |
| SCHEMBL8408707 | 0.70 | ALDH1A1 (0.36) | SMN1; SMN2TSHREPHX1GRM4 | |
| SCHEMBL5897133 | 0.70 | ALDH1A1 (0.36) | SMN1; SMN2TSHREPHX1GRM4 | |
| SCHEMBL5897120 | 0.70 | ALDH1A1 (0.36) | SMN1; SMN2TSHREPHX1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |