Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 9/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498687 | 0.82 | GSR (0.42) | GSRBCHECA2 | |
| Fumaric Acid SCHEMBL9795361 | 0.79 | GSR (0.39) | GSRBCHE | |
| SCHEMBL9795356 | 0.77 | GSR (0.38) | GSRBCHE | |
| Fumaric Acid SCHEMBL9795349 | 0.76 | GSR (0.37) | GSRBCHE | |
| SCHEMBL10567442 | 0.73 | GSR (0.56) | GSRBCHECA2ALDH1A1 | |
| SCHEMBL9795186 | 0.73 | GSR (0.51) | GSRBCHECA2ALDH1A1 | |
| SCHEMBL9795326 | 0.72 | TDP1 (0.61) | GSRTDP1BCHEALDH1A1 | |
| SCHEMBL8957422 | 0.70 | GSR (0.71) | GSRBCHECA2ALDH1A1 | |
| SCHEMBL10570604 | 0.69 | GSR (0.50) | GSRBCHECA2ALDH1A1 | |
| Fumaric Acid SCHEMBL9795374 | 0.69 | GSR (0.38) | GSRBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |