Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795501 | 0.87 | MAPT (0.56) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL9795496 | 0.85 | MAPT (0.54) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL9795499 | 0.84 | MAPT (0.53) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL9795475 | 0.83 | MAPT (0.65) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL9795520 | 0.82 | MAPT (0.42) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9795390 | 0.79 | USP10 (0.41) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL29098641 | 0.74 | KDM4E (0.54) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL30345112 | 0.74 | KDM4E (0.54) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL7375948 | 0.73 | KDM4E (0.57) | MEN1KMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL9795365 | 0.73 | CYP1A2 (0.49) | MAPTMEN1KMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057142-A | Herbicidal thiazolecarboxamide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |
| EP-0422470-A2 | Thiazolcarboxylic acid amide derivatives | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |