Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795501 | 0.85 | MAPT (0.56) | CYP1A2CYP2C9CYP2C19RECQLMAPT | |
| SCHEMBL9795455 | 0.81 | P2RY1 (0.56) | CYP1A2CYP2C19MAPTALDH1A1KDM4E | |
| SCHEMBL9795481 | 0.81 | MAOB (0.49) | MAPTALDH1A1L3MBTL1HTT | |
| SCHEMBL9795446 | 0.78 | NPSR1 (0.64) | CYP1A2CYP2C9CYP2C19MAPTKDM4E | |
| SCHEMBL9795496 | 0.74 | MAPT (0.54) | CYP1A2CYP2C9CYP2C19RECQLMAPT | |
| SCHEMBL9795461 | 0.73 | MAPT (0.53) | CYP1A2CYP2C9CYP2C19RECQLMAPT | |
| SCHEMBL9795499 | 0.73 | MAPT (0.53) | CYP1A2CYP2C9CYP2C19RECQLMAPT | |
| SCHEMBL11587313 | 0.72 | ALDH1A1 (0.61) | CYP1A2CYP2C9CYP2C19RECQLMAPT | |
| SCHEMBL9795475 | 0.72 | MAPT (0.65) | CYP1A2CYP2C9CYP2C19MAPTALDH1A1 | |
| SCHEMBL8177633 | 0.72 | KDM4E (0.62) | CYP1A2CYP2C9CYP2C19KDM4EP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057142-A | Herbicidal thiazolecarboxamide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |