Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900410 | 0.81 | DNM1 (0.61) | DNM1CYP1A2CYP2D6GAACYP3A4 | |
| SCHEMBL8398220 | 0.80 | DNM1 (0.69) | DNM1GAAHDAC3HDAC4HDAC1 | |
| SCHEMBL8398925 | 0.78 | DNM1 (0.72) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3005968 | 0.78 | DNM1 (0.72) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10964167 | 0.78 | DNM1 (0.72) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6729860 | 0.78 | DNM1 (0.72) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL74996 | 0.78 | DNM1 (0.72) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3411287 | 0.78 | DNM1 (0.72) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL74483 | 0.78 | DNM1 (0.72) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL76373 | 0.78 | DNM1 (0.72) | DNM1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |