Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GRK2 | P25098 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499217 | 0.91 | ALDH1A1 (0.38) | ALDH1A1POLBGRK2L3MBTL1 | |
| SCHEMBL9501604 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CYP1A2 | |
| SCHEMBL9499257 | 0.82 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL9497858 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2A | |
| Fumaric Acid SCHEMBL9795166 | 0.77 | ALDH1A1 (0.34) | ALDH1A1CYP1A2 | |
| SCHEMBL9499920 | 0.74 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL9501649 | 0.73 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL19449163 | 0.70 | ALDH1A1 (0.45) | ALDH1A1CYP1A2NPC1HPGDRAB9A | |
| SCHEMBL9498497 | 0.70 | CA1 (0.40) | CYP1A2HPGDSMN1; SMN2MEN1LMNA | |
| SCHEMBL9795314 | 0.70 | ALDH1A1 (0.37) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |