Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | FABP1 | P07148 | 1/20 | 0.49 |
| ▸ | FABP6 | P51161 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317275 | 0.83 | KCNQ3 (0.55) | MAP4K4SMN1; SMN2APPL3MBTL1MEN1 | |
| SCHEMBL29972915 | 0.81 | MAP4K4 (0.54) | MAP4K4SMN1; SMN2APPFABP1FABP6 | |
| SCHEMBL15347854 | 0.78 | HSD17B10 (0.57) | MAP4K4SMN1; SMN2APPBACE1L3MBTL1 | |
| SCHEMBL5759562 | 0.77 | POLB (0.55) | MAP4K4SMN1; SMN2LMNAPOLBMEN1 | |
| SCHEMBL12820608 | 0.76 | FABP1 (0.55) | MAP4K4SMN1; SMN2APPFABP1FABP6 | |
| SCHEMBL10787515 | 0.75 | MAPK1 (0.49) | MAP4K4SMN1; SMN2BACE1LMNAL3MBTL1 | |
| SCHEMBL20271334 | 0.74 | HRH4 (0.62) | MAP4K4SMN1; SMN2FABP1FABP6MEN1 | |
| SCHEMBL15587794 | 0.73 | MAP4K4 (1.00) | MAP4K4APP | |
| SCHEMBL30885179 | 0.73 | RAB9A (0.66) | MAP4K4SMN1; SMN2APPFABP1FABP6 | |
| SCHEMBL19553834 | 0.73 | RAB9A (0.66) | MAP4K4SMN1; SMN2APPFABP1FABP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199951-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-3-NITRO-6-(4-FLUOROBENZYLAMINO) PYRIDINE AND OF 2-AMINO-3-CARBETHOXYAMINO-6-(4-FLUOROBENZYLAMINO) PYRIDINE | ASTA Pharma Aktiengesellschaft (DE) | 1991-01-23 | — | — | EP | disclosed |
| US-4785110-A | Process for the production of 2-amino-3-nitro-6-(4-fluorobenzylamino)-pyridine | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| US-4554281-A | 2-Amino-3-acylamino-6-benzylamino-pyridine-derivative having antiepileptic action | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-11-19 | — | — | US | disclosed |