Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL10988914 | 0.97 | ALDH1A1 (0.45) | ALDH1A1TSHRTDP1TP53CYP3A4 | |
| Styrene SCHEMBL8425450 | 0.92 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1MAPTRAB9A | |
| Acrylonitrile SCHEMBL603162 | 0.91 | AKT1 (0.39) | ALDH1A1TSHRPDE4APDE4BPDE4C | |
| Acrylonitrile SCHEMBL8673664 | 0.91 | AKT1 (0.39) | ALDH1A1TSHRPDE4APDE4BPDE4C | |
| Styrene SCHEMBL10941975 | 0.91 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1CYP3A4MAPT | |
| Styrene SCHEMBL9567884 | 0.89 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1TP53CYP3A4 | |
| Styrene SCHEMBL315930 | 0.89 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1TP53CYP3A4 | |
| Acrylonitrile SCHEMBL9079608 | 0.87 | PDE4A (0.37) | ALDH1A1TSHRPDE4APDE4BPDE4C | |
| Styrene SCHEMBL9250299 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1TP53CYP3A4 | |
| Styrene SCHEMBL1067899 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186926-B1 | METHOD FOR THE PREPARATION OF GRAFT COPOLYMERS BY EMULSION COPOLYMERIZATION | MONTEDIPE S.r.l. (IT) | 1991-01-16 | — | — | EP | claimed |
| CN-112480583-B | Blend optical film with thermodynamic stability and preparation method thereof | 聚纶材料科技（深圳）有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-112673141-A | Building material board and method for manufacturing building | 株式会社钟化 | 2021-04-16 | — | — | CN | disclosed |
| CN-112480583-A | Blend optical film with thermodynamic stability and preparation method thereof | 聚纶材料科技（深圳）有限公司 | 2021-03-12 | — | — | CN | disclosed |
| US-10273355-B2 | Thermoplastic resin composition | LOTTE ADVANCED MATERIALS CO., LTD. (KR) | 2019-04-30 | — | — | US | disclosed |
| CN-103613877-B | High heat-proof ABS resin composition suitable for blow molding and preparation method thereof | 上海锦湖日丽塑料有限公司 | 2017-09-19 | — | — | CN | disclosed |
| US-20160060446-A1 | Thermoplastic Resin Composition | LOTTE ADVANCED MATERIALS CO., LTD. (KR) | 2016-03-03 | — | — | US | disclosed |
| CN-103476834-A | Polyorganosiloxane latex, graft copolymer using same, thermoplastic resin composition, and molded article | MITSUBISHI RAYON CO | 2013-12-25 | — | — | CN | disclosed |
| CN-85103737-B | Process for producing alpha-methylstyrene-acrylonitrile heat-resistant copolymer | 日本合成橡胶株式会社 | 1988-11-02 | — | — | CN | disclosed |
| US-4302378-A | GRAFT POLYMER WITH A THERMOPLASTIC RESIN AND A PERFLUOROALKANE ACID OR DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-24 | — | — | US | disclosed |