Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178412 | 0.73 | ATM (0.48) | ATMTRIM24TRIM33ALDH1A1GAA | |
| SCHEMBL22076913 | 0.69 | ATM (0.48) | ATMTRIM24TRIM33POLBALDH1A1 | |
| SCHEMBL31273663 | 0.69 | TRIM24 (0.48) | ATMTRIM24TRIM33KDM4EPOLB | |
| SCHEMBL28845024 | 0.69 | TRIM24 (0.44) | ATMTRIM24TRIM33POLBALDH1A1 | |
| SCHEMBL27554082 | 0.69 | ATM (0.44) | ATMTRIM24TRIM33DRD2DRD4 | |
| Maleic Acid SCHEMBL9469974 | 0.69 | SLC6A2 (0.52) | ATMKDM4EALDH1A1KMT2ACYP1A2 | |
| SCHEMBL3195414 | 0.67 | TRIM24 (0.46) | ATMTRIM24TRIM33KDM4EALDH1A1 | |
| SCHEMBL10366987 | 0.67 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL14397853 | 0.67 | ATM (0.42) | ATMTRIM24TRIM33POLBALDH1A1 | |
| SCHEMBL14397828 | 0.67 | ATM (0.46) | ATMTRIM24TRIM33POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039687-A | Learning enhancement, cognition activation | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-4900742-A | N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4752610-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-06-21 | — | — | US | disclosed |