Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 19/20 | 0.81 |
| ▸ | CA2 | P00918 | 19/20 | 0.81 |
| ▸ | CA9 | Q16790 | 13/20 | 0.81 |
| ▸ | CA12 | O43570 | 5/20 | 0.67 |
| ▸ | CA3 | P07451 | 3/20 | 0.67 |
| ▸ | CA6 | P23280 | 3/20 | 0.67 |
| ▸ | CA5A | P35218 | 3/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.67 |
| ▸ | CA7 | P43166 | 2/20 | 0.66 |
| ▸ | CA4 | P22748 | 1/20 | 0.66 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.66 |
| ▸ | AKT1 | P31749 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796165 | 0.85 | CA1 (0.76) | CA1CA2CA9CA12CA3 | |
| SCHEMBL283024 | 0.80 | CA1 (1.00) | CA1CA2CA9CA12CA3 | |
| SCHEMBL23752535 | 0.80 | CA1 (1.00) | CA1CA2CA9CA12CA3 | |
| SCHEMBL9796270 | 0.79 | CA1 (1.00) | CA1CA2CA9CA12CA3 | |
| SCHEMBL9795893 | 0.79 | CA1 (1.00) | CA1CA2CA9CA12CA3 | |
| Benzolamide SCHEMBL3497931 | 0.79 | CA1 (1.00) | CA1CA2CA9CA12CA3 | |
| SCHEMBL5389518 | 0.77 | MEN1 (0.74) | CA1CA2CA9CA12CA3 | |
| SCHEMBL5388834 | 0.76 | KMT2A (0.59) | CA1CA2CA9 | |
| SCHEMBL328336 | 0.76 | AKT1 (1.00) | CA1CA2CA9CA12CA3 | |
| SCHEMBL4965134 | 0.76 | CA1 (1.00) | CA1CA2CA9CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990523-A | Treatment of chronic inflammatory joint disease with arylsulfonamides | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-02-05 | — | — | US | disclosed |
| WO-1990015600-A2 | TREATMENT OF CHRONIC INFLAMMATORY JOINT DISEASE WITH ARYLSULFONAMIDES | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-27 | — | — | WO | disclosed |