SCHEMBL9796348

SCHEMBL9796348

C=CCSC(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.33
CTSB P07858 1/20 0.33
NOTUM Q6P988 2/20 0.33
NSD2 O96028 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
PKM P14618 1/20 0.31
APEX1 P27695 1/20 0.31
CASP3 P42574 1/20 0.31
RECQL P46063 1/20 0.31
CASP6 P55212 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9497504 0.83
SCHEMBL9540486 0.82 HPGD (0.49) ALDH1A1POLBP2RX7
Ethylene SCHEMBL9423310 0.81 TDP1 (0.39) TDP1CTSBNOTUMNSD2ALDH1A1
SCHEMBL29576263 0.81 TDP1 (0.40) TDP1CTSBNOTUMNSD2ALDH1A1
SCHEMBL1807362 0.81 TDP1 (0.52) TDP1CTSBNOTUMNSD2ALDH1A1
SCHEMBL9423041 0.81 TDP1 (0.40) TDP1CTSBNOTUMNSD2ALDH1A1
SCHEMBL9168174 0.81 TDP1 (0.40) TDP1CTSBNOTUMNSD2ALDH1A1
SCHEMBL9423187 0.80 TDP1 (0.38) TDP1CTSBNOTUMNSD2ALDH1A1
SCHEMBL6465173 0.80 LMNA (0.47) TDP1CTSBNOTUMNSD2ALDH1A1
SCHEMBL9796351 0.80 XPA (0.32) TDP1CTSBNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5041156-A 3-aryluracils for the control of weeds CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed