Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 20/20 | 0.76 |
| ▸ | IKBKE | Q14164 | 8/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204351 | 0.91 | TBK1 (0.76) | TBK1IKBKEKDM4ENPC1ABCC4 | |
| SCHEMBL19197555 | 0.89 | TBK1 (0.79) | TBK1IKBKEKDM4ENPC1ABCC4 | |
| SCHEMBL19196860 | 0.87 | TBK1 (0.80) | TBK1IKBKEKDM4ENPC1ABCC4 | |
| SCHEMBL19181474 | 0.86 | TBK1 (1.00) | TBK1IKBKEKDM4ENPC1ABCC4 | |
| SCHEMBL19182344 | 0.86 | TBK1 (0.77) | TBK1IKBKEKDM4ENPC1ABCC4 | |
| SCHEMBL19180387 | 0.85 | TBK1 (1.00) | TBK1IKBKE | |
| SCHEMBL19200757 | 0.84 | TBK1 (1.00) | TBK1IKBKEKDM4ENPC1ABCC4 | |
| SCHEMBL19180142 | 0.83 | TBK1 (1.00) | TBK1IKBKEKDM4ENPC1ABCC4 | |
| SCHEMBL19181488 | 0.83 | TBK1 (1.00) | TBK1IKBKE | |
| SCHEMBL19182116 | 0.83 | TBK1 (1.00) | TBK1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3086884-A | — | — | None | — | — | JP | disclosed |
| JP-H0386884-A | BENZOPYRANOPYRIDINE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1991-04-11 | — | — | JP | disclosed |