Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 9/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.51 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796839 | 1.00 | BDKRB2 (0.65) | BDKRB2OPRD1OPRM1F2NMUR2 | |
| SCHEMBL29973203 | 0.97 | BDKRB2 (0.67) | BDKRB2OPRD1OPRM1F2NMUR2 | |
| SCHEMBL11169796 | 0.97 | BDKRB2 (0.67) | BDKRB2OPRD1OPRM1F2NMUR2 | |
| SCHEMBL9739197 | 0.97 | BDKRB2 (0.61) | BDKRB2OPRD1OPRM1F2NMUR2 | |
| SCHEMBL9739189 | 0.97 | BDKRB2 (0.61) | BDKRB2OPRD1OPRM1F2NMUR2 | |
| SCHEMBL29973237 | 0.96 | BDKRB2 (0.64) | BDKRB2OPRD1OPRM1F2NMUR2 | |
| SCHEMBL17887567 | 0.96 | BDKRB2 (0.64) | BDKRB2OPRD1OPRM1F2NMUR2 | |
| Bradykinin SCHEMBL7949684 | 0.95 | BDKRB2 (0.67) | BDKRB2OPRD1OPRM1F2NMUR2 | |
| Bradykinin SCHEMBL7949679 | 0.95 | BDKRB2 (0.67) | BDKRB2OPRD1OPRM1F2NMUR2 | |
| SCHEMBL29750398 | 0.95 | BDKRB2 (0.62) | BDKRB2OPRD1OPRM1NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243429-B1 | D-LUCIFERIN DERIVATIVES AND THEIR USE | Geiger, Reinhard, Dr. (DE) | 1991-01-23 | — | — | EP | disclosed |
| EP-0243429-A1 | D-LUCIFERIN DERIVATIVES AND THEIR USE. | GEIGER REINHARD DR (DE) | 1987-11-04 | — | — | EP | disclosed |
| WO-1987002667-A1 | D-LUCIFERIN DERIVATIVES AND THEIR USE | GEIGER REINHARD (DE) | 1987-05-07 | — | — | WO | disclosed |