Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917423 | 0.86 | CYP2D6 (0.56) | GAAKMT2AMEN1MGAMSI | |
| SCHEMBL31126820 | 0.86 | GAA (0.45) | GAAKMT2AMEN1MGAMSI | |
| SCHEMBL14842764 | 0.86 | GAA (0.41) | GAAKMT2AMEN1MGAMSI | |
| SCHEMBL10810868 | 0.85 | HRH4 (0.44) | GAAKMT2AMEN1HRH4HRH3 | |
| SCHEMBL3373145 | 0.84 | GAA (0.45) | GAAKMT2AMEN1MGAMSI | |
| SCHEMBL13681841 | 0.84 | GAA (0.45) | GAAKMT2AMEN1MGAMSI | |
| SCHEMBL4819904 | 0.84 | GAA (0.45) | GAAKMT2AMEN1MGAMSI | |
| SCHEMBL24401471 | 0.83 | ACHE (0.46) | GAAKMT2AMEN1HRH4HRH3 | |
| SCHEMBL28477455 | 0.83 | GAA (0.39) | GAAKMT2AMEN1MGAMSI | |
| SCHEMBL9117583 | 0.82 | GAA (0.46) | GAAKMT2AMEN1MGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202523-B1 | PROCESS FOR THE PREPARATION OF 1,3-DI(ALKOXYCARBONYLAMINO) PROPANE | BASF Aktiengesellschaft (DE) | 1991-01-30 | — | — | EP | disclosed |
| US-4672137-A | Preparation of 1,3-di(alkoxycarbonylamino)propanes | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-09 | — | — | US | disclosed |
| EP-0202523-A2 | Process for the preparation of 1,3-di(alkoxycarbonylamino) propane | BASF Aktiengesellschaft (DE) | 1986-11-26 | — | — | EP | disclosed |