Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176481 | 0.80 | PTGS2 (0.45) | PTGS2ADRA2CKDM4ELMNAADRA2A | |
| SCHEMBL16168604 | 0.80 | PTGS2 (0.45) | PTGS2ADRA2CKDM4ELMNAADRA2A | |
| SCHEMBL13177031 | 0.80 | PTGS2 (0.45) | PTGS2ADRA2CKDM4ELMNAADRA2A | |
| SCHEMBL2163297 | 0.78 | HPGD (0.47) | PTGS2ADRA2CKDM4ELMNAADRA2A | |
| Ammonia Solution, Strong SCHEMBL11508344 | 0.78 | PTGS2 (0.43) | PTGS2ADRA2CKDM4ELMNAADRA2A | |
| SCHEMBL4813777 | 0.78 | PTGS2 (0.43) | PTGS2ADRA2CKDM4ELMNAADRA2A | |
| SCHEMBL16594346 | 0.76 | PTGS2 (0.42) | PTGS2ADRA2CKDM4ELMNAADRA2A | |
| SCHEMBL10628842 | 0.76 | PTGS2 (0.47) | PTGS2ADRA2CKDM4ELMNAADRA2A | |
| SCHEMBL27543581 | 0.76 | PTGS2 (0.52) | PTGS2KDM4ELMNAHIF1AHPGD | |
| SCHEMBL1814078 | 0.74 | PTGS2 (0.41) | PTGS2ADRA2CKDM4ELMNAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410380-A2 | Novel process for the synthesis of 2-fluoro-1-olefins | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-01-30 | — | — | EP | disclosed |