⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530314 | 0.70 | — | — | |
| Formaldehyde SCHEMBL28212738 | 0.70 | KDM4E (0.45) | — | |
| SCHEMBL1532454 | 0.69 | — | — | |
| SCHEMBL29109510 | 0.69 | — | — | |
| SCHEMBL29419501 | 0.68 | — | — | |
| SCHEMBL175354 | 0.68 | — | — | |
| SCHEMBL2763051 | 0.68 | — | — | |
| SCHEMBL4950388 | 0.68 | — | — | |
| SCHEMBL5925751 | 0.68 | — | — | |
| SCHEMBL980904 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722714-B2 | Oxazolidine derivatives as NMDA antagonists | The Honk Kong University of Science and Technology (CN) | 2014-05-13 | — | — | US | disclosed |
| US-8642788-B2 | Activators of executioner procaspases 3, 6 and 7 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-02-04 | — | — | US | disclosed |
| US-20110144168-A1 | OXAZOLIDINE DERIVATIVES AS NMDA ANTAGONISTS | BIOTECHNOLOGY RESEARCH CORPORATION LIMITED (CN) | 2011-06-16 | — | — | US | disclosed |
| US-20110021522-A1 | ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2237784-A1 | ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 | The Regents of the University of California (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009092324-A1 | OXAZOLIDINE DERIVATIVES AS NMDA ANTAGONISTS | HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009089508-A1 | ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-07-16 | — | — | WO | disclosed |