⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051474 | 0.74 | KDM4E (0.43) | — | |
| SCHEMBL17530314 | 0.70 | — | — | |
| SCHEMBL24534291 | 0.70 | CYP1A2 (0.54) | — | |
| SCHEMBL981305 | 0.70 | — | — | |
| Methyl Alcohol SCHEMBL27778739 | 0.70 | KDM4E (0.50) | — | |
| SCHEMBL2213273 | 0.69 | — | — | |
| SCHEMBL27642043 | 0.69 | KMT2A (0.51) | — | |
| SCHEMBL1966649 | 0.69 | CA1 (0.41) | — | |
| SCHEMBL31064854 | 0.69 | — | — | |
| SCHEMBL12379211 | 0.69 | MAPT (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107619447-A | A kind of polyvinyl ingredient of solid catalyst of synthesizing super high molecular weight and preparation method and application | 谢炳 | 2018-01-23 | — | — | CN | claimed |
| CN-1990478-B | 6-aryl-3-substituted methylene pyranone compounds, preparation process and use thereof | ZHEJIANG HISUN PHARM CO LTD | 2011-08-31 | — | — | CN | claimed |
| CN-1990478-A | 6-aryl-3-substituted methylene pyranone compounds, preparation process and use thereof | ZHEJIANG HISUN NATURELITE PHAR (CN) | 2007-07-04 | — | — | CN | claimed |
| US-11691963-B2 | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors | AJAX THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| CN-111065265-B | Herbicidal composition | 蓝宝迪有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-109868225-B | Trichoderma asperellum N-8-2 and application thereof | 广西壮族自治区农业科学院植物保护研究所 | 2022-11-01 | — | — | CN | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| US-10745674-B2 | Polyketide synthase variants and uses thereof | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190142866-A1 | POROUS CARBON PARTICLES FOR USE IN THE TREATMENT OR PREVENTION OF LIVER DISEASE | HOWELL CAROL ANGELA (GB) | 2019-05-16 | — | — | US | disclosed |
| US-10188592-B2 | 2-pyrones | MERCK PATENT GMBH (DE) | 2019-01-29 | — | — | US | disclosed |
| CN-107793353-A | Milk tree alkaloid compound and its application | 中山大学 | 2018-03-13 | — | — | CN | disclosed |
| WO-2004018552-A1 | USE OF COMPOSITIONS CONTAINING 4-HYDROXY-2-PYRONES FOR STABILISING ORGANIC PLASTICS CONTAINING HALOGEN | REAGENS DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | WO | disclosed |
| WO-2002057418-A2 | METHODS OF PRODUCING POLYKETIDE SYNTHASE MUTANTS AND COMPOSITIONS AND USES THEREOF | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2002-07-25 | — | — | WO | disclosed |
| US-6288109-B1 | Pyranones, method for the production and use thereof | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 2001-09-11 | — | — | US | disclosed |
| CN-1299359-A | Benzofurylpyrone derivatives | TEIJIN LTD (JP) | 2001-06-13 | — | — | CN | disclosed |
| WO-2001007579-A2 | METHODS AND COMPOSITIONS FOR DETERMINING ENZYMATIC ACTIVITY | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2001-02-01 | — | — | WO | disclosed |
| EP-0300326-A1 | Hydroxypolyimides and high temperature resistant positive photoresists | HOECHST CELANESE CORPORATION (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4311782-A | POLYETHER OF ORTHOCARBOXYLIC ESTER | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-19 | — | — | US | disclosed |
| US-4247611-A | ACETAL RESIN, ACID DONER | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-27 | — | — | US | disclosed |
| US-4101323-A | Radiation-sensitive copying composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |