Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050902 | 0.88 | PARP10 (0.65) | PARP10PARP3ALDH1A1CYP2A6KDM4E | |
| SCHEMBL1663469 | 0.88 | PARP10 (0.65) | PARP10PARP3ALDH1A1CYP2A6KDM4E | |
| SCHEMBL296908 | 0.88 | ALDH1A1 (0.65) | PARP10PARP3ALDH1A1KDM4ELMNA | |
| SCHEMBL92255 | 0.85 | ALDH1A1 (0.69) | ALDH1A1CYP2A6KDM4EALDH1A3HSD17B10 | |
| Ethylene SCHEMBL29144706 | 0.83 | ALDH1A1 (0.65) | ALDH1A1CYP2A6KDM4EALDH1A3HSD17B10 | |
| SCHEMBL17445756 | 0.81 | ALDH1A1 (0.55) | PARP10PARP3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20024709 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| Benzene SCHEMBL7538692 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP2A6KDM4ELMNASMN1; SMN2 | |
| SCHEMBL16202966 | 0.79 | ALDH1A1 (0.45) | PARP10PARP3ALDH1A1CYP2A6KDM4E | |
| SCHEMBL97639 | 0.79 | ALDH1A1 (0.59) | PARP10PARP3ALDH1A1CYP2A6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981978-A | Reaction products of imidazole on pyrazole derivatives and 4-isopropenyl-1-cyclohexene-1-carboxaldehyde | THE DOW CHEMICAL COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
| US-4927932-A | Reaction products of pyrimidine, pyridazine and 4-isopropenyl-1-cyclohexene-1-carboxaldehyde | THE DOW CHEMICAL COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4831137-A | Reaction products of pteridine and 4-isopropenyl-1-cyclohexene-1-carboxaldehyde | THE DOW CHEMICAL COMPANY (US) | 1989-05-16 | — | — | US | disclosed |
| US-4755600-A | Reaction products of pyrazine, pyridine, quinoline and quinoxaline derivatives and 4-isopropenyl-1-cyclohexene-1-carboxaldehyde | THE DOW CHEMICAL COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4680347-A | Thermosettable polystyrylpyrazine polymers terminated with ethylenically unsaturated groups and cured products therefrom | THE DOW CHEMICAL COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| EP-0220204-A1 | THERMOSETTABLE POLYSTYRYLPYRIDINE PREPOLYMER TERMINATED WITH ETHYLENICALLY UNSATURATED GROUPS AND CURED PRODUCTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
| US-4629770-A | Thermosettable polystyrylpyrazine polymers terminated with ethylenically unsaturated groups and cured products therefrom | THE DOW CHEMICAL COMPANY (US) | 1986-12-16 | — | — | US | disclosed |
| WO-1986006386-A1 | THERMOSETTABLE POLYSTYRYLPYRIDINE PREPOLYMER TERMINATED WITH ETHYLENICALLY UNSATURATED GROUPS AND CURED PRODUCTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1986-11-06 | — | — | WO | disclosed |
| US-4575542-A | Thermosettable polystyrylpyridine prepolymer terminated with ethylenically unsaturated groups and cured products therefrom | THE DOW CHEMICAL COMPANY (US) | 1986-03-11 | — | — | US | disclosed |