Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.51 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | BAD | Q92934 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10496539 | 1.00 | GRIK1 (0.51) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9797931 | 0.81 | GRIK1 (0.55) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10496436 | 0.81 | GRIK1 (0.55) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL16105818 | 0.79 | AHR (0.52) | RXRANR4A2KDM4EMDM4ALDH1A1 | |
| SCHEMBL2291774 | 0.79 | GRIK1 (0.58) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL16105690 | 0.79 | AHR (0.52) | RXRANR4A2KDM4EMDM4ALDH1A1 | |
| SCHEMBL16105692 | 0.79 | AHR (0.52) | RXRANR4A2KDM4EMDM4ALDH1A1 | |
| SCHEMBL13554389 | 0.79 | GRIK1 (0.58) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29542528 | 0.79 | GRIK1 (0.58) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1019981 | 0.79 | GRIK1 (0.58) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275501-B1 | PROCESS FOR THE PREPARATION OF (Z)-2-(2-ARYLETHENYL)-ARYLCARBOXYLIC ACIDS | BASF Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4857658-A | Preparation of (Z)-2-(2-arylethenyl)arylcarboxylic acids | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | disclosed |
| EP-0275501-A1 | Process for the preparation of (Z)-2-(2-arylethenyl)-arylcarboxylic acids | BASF Aktiengesellschaft (DE) | 1988-07-27 | — | — | EP | disclosed |