Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798392 | 1.00 | ALDH3A1 (0.46) | ALDH3A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9798677 | 0.93 | MAPT (0.40) | ALDH3A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9798671 | 0.93 | MAPT (0.40) | ALDH3A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9799213 | 0.92 | MAPT (0.40) | ALDH3A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9799209 | 0.92 | MAPT (0.40) | ALDH3A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9798719 | 0.91 | MAPT (0.39) | ALDH3A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9798341 | 0.91 | MAPT (0.39) | ALDH3A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9798642 | 0.91 | MAPT (0.39) | ALDH3A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9798511 | 0.91 | MAPT (0.39) | ALDH3A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9798711 | 0.91 | MAPT (0.39) | ALDH3A1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411103-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK PATENT GmbH (DE) | 1991-02-06 | — | — | EP | disclosed |
| WO-1990009616-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |