Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798446 | 1.00 | MAPT (0.47) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9798356 | 0.96 | MAPT (0.50) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9798595 | 0.87 | MEN1 (0.50) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL9798589 | 0.87 | MEN1 (0.50) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL9799330 | 0.86 | MAPT (0.43) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9799326 | 0.86 | MAPT (0.43) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL13236059 | 0.86 | MAPT (0.50) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9798630 | 0.85 | ALDH3A1 (0.44) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL9798622 | 0.85 | ALDH3A1 (0.44) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL9798875 | 0.84 | MAPT (0.54) | MAPTALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411103-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK PATENT GmbH (DE) | 1991-02-06 | — | — | EP | disclosed |
| WO-1990009616-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |