Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29277865 | 0.91 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL28380883 | 0.89 | ALDH1A1 (0.34) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL6013874 | 0.88 | ALDH1A1 (0.36) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| Water SCHEMBL10732835 | 0.87 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL29192600 | 0.87 | TSHR (0.41) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL28723020 | 0.85 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL7625494 | 0.85 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL19490 | 0.85 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL12002785 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| Iodide SCHEMBL7702886 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193406-B1 | DEVICE FOR CONTROLLING INCONTINENCE | MEDTRONIC, INC. (US) | 1991-02-20 | — | — | EP | disclosed |