Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798982 | 1.00 | ALDH1A1 (0.41) | ALDH1A1PPARANPC1RAB9AKMT2A | |
| SCHEMBL9531977 | 0.92 | ALDH1A1 (0.41) | ALDH1A1PPARASMPD1 | |
| SCHEMBL9799444 | 0.91 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AKMT2AMGLL | |
| SCHEMBL9799452 | 0.91 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AKMT2AMGLL | |
| SCHEMBL9532943 | 0.90 | ALDH1A1 (0.40) | ALDH1A1PPARAKMT2A | |
| Bromide SCHEMBL9529680 | 0.89 | ALDH1A1 (0.39) | ALDH1A1PPARA | |
| SCHEMBL9529222 | 0.88 | ALDH1A1 (0.38) | ALDH1A1PPARA | |
| Bromide SCHEMBL9528346 | 0.87 | ALDH1A1 (0.38) | ALDH1A1PPARA | |
| SCHEMBL9529646 | 0.86 | ALDH1A1 (0.37) | ALDH1A1PPARASMPD1 | |
| SCHEMBL9529746 | 0.86 | SMN1; SMN2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |