Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799747 | 0.84 | CYP19A1 (0.58) | CYP3A4CYP19A1MAOAMAOBTDP1 | |
| SCHEMBL9799795 | 0.82 | CYP19A1 (0.63) | TP53CYP19A1MAOAMAOBSIGMAR1 | |
| SCHEMBL841378 | 0.79 | CYP19A1 (0.84) | CYP3A4CYP19A1MAOAMAOBSIGMAR1 | |
| SCHEMBL29437072 | 0.79 | MAOB (0.71) | CYP3A4CYP19A1MAOAMAOBTDP1 | |
| SCHEMBL1026806 | 0.79 | MAOB (0.71) | CYP3A4CYP19A1MAOAMAOBTDP1 | |
| SCHEMBL9799262 | 0.78 | CYP19A1 (0.63) | CYP19A1MAOAMAOBSIGMAR1 | |
| SCHEMBL9798986 | 0.77 | MAOB (0.83) | CYP19A1MAOAMAOBSIGMAR1 | |
| SCHEMBL4248652 | 0.77 | NQO1 (0.67) | CYP3A4TSHRTDP1SIGMAR1NQO1 | |
| SCHEMBL7004918 | 0.77 | CYP19A1 (0.67) | CYP3A4CYP19A1MAOAMAOB | |
| SCHEMBL12040583 | 0.76 | SIGMAR1 (0.61) | TDP1SIGMAR1NQO1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015762-A | Alkoxy substituted ureas as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| EP-0041145-B1 | ARALKYL-PHENYL UREAS AND THEIR HERBICIDAL COMPOSITIONS | BASF Aktiengesellschaft (DE) | 1984-12-19 | — | — | EP | disclosed |
| US-4422871-A | Aralkylphenylureas and herbicides containing these | BASF AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |
| EP-0041145-A2 | Aralkyl-phenyl ureas and their herbicidal compositions | BASF Aktiengesellschaft (DE) | 1981-12-09 | — | — | EP | disclosed |